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Southwest Virginia MS Support Group

 

 
   
 

CSF Oligoclonal Banding - Series: Procedure, part 3

SOURCE: www.NLM.NIH.gov

 

 

 

 

 

Both the samples are added to a gel, which is then filtered through a cartridge. The gel separates the proteins in each sample and the lab looks for oligoclonal banding.

 

Reults:

 

Normal:

One or less bandings found in the CSF is normal.

   

Abnormal:

Results are considered abnormal if there are 2 or more bandings found in the CSF and not in the blood serum. This may indicate multiple sclerosis (MS). CSF oligoclonal bands are found in 83% to 94% of patients with definite MS. Other causes of oligoclonal banding in CSF include encephalitis, meningitis, Guillain-Barré syndrome, polyneuritis, headache, and other conditions.